How Gaming Helped AIDS Researchers

September 19, 2011 -

A research paper published Sunday by the journal Nature Structural & Molecular Biology details how the online game Foldit successfully mapped a protein-cutting enzyme from a particular AIDS-like virus found in rhesus monkeys. This enzyme apparently helps the virus spread and to counteract it, its exact molecular structure had to be mapped. This task had been impossible until crowd sourcing came along.

University of Washington chemist Firas Khatib and computer scientist Seth Cooper handled the Foldit program's design and implementation. In a statement issued to the press, Cooper said that people are what truly made the difference in solving this monumental problem.

"People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans."

Khatib spoke with Seattle Weekly about the project last night, saying that this breakthrough was "huge" for science more than for aids because it could prove to be helpful to researchers throughout the world who could use the extra help with complex problems.

"This is the first case that were aware of where online gamers solved a scientific problem that hadn't been able to be cracked by all scientific methods developed," Khatib says. "My big hope is that other scientists with challenging problems they can't solve and have been banging their heads over for years will come to us and say 'can you help?'"

Khatib says that Foldit's success comes mostly from being an online competitive game. The game has around 236,000 registered players since it launched in 2008. By putting real-time scores and rankings that change based on how well-designed players make their molecular structures, the program takes advantage of the competitive nature of gaming to accomplish something real.

"If we had just posted it as 'hey, can you help us?' I think we would have gotten a few volunteers and some would have stuck around," Khatib says. "But the fact that there is this competitive aspect, that unleashes a lot more motivation."

The next step, says researchers, is for Foldit players to create new genetic structures related to the Flu virus.

"We want to have players design a protein that will inhibit the flu virus," Khatib says. "This is just the start."

Source: Seattle Weekly


 
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InfophileThat's what they call it? I always called it hydroxic acid...09/21/2014 - 11:57am
MaskedPixelanteProbably dihydrogen monoxide, the most dangerous substance in the universe.09/21/2014 - 10:14am
james_fudgewell I hope he called the police so they can let us all know.09/21/2014 - 9:07am
quiknkoldIt's pretty gnarly. Depending on what it is, it could be worse than white powder or a fake bomb.09/21/2014 - 9:06am
james_fudgeI just looked it up on UPS.com09/21/2014 - 8:56am
james_fudgeand expensive for an American to ship to London.09/21/2014 - 8:55am
E. Zachary KnightThat is pretty scary. Would have been worse if it were a fake bomb or white powder.09/21/2014 - 8:49am
quiknkoldThere's some more tweets regarding it with more pictures09/21/2014 - 8:09am
quiknkoldMilo Yiannopoulos was mailed a syringe filled with clear liquid. He claims it's anti gamergate harassment. Mentioned on his twitter twitter.com/Nero/status/51366668391625523209/21/2014 - 8:07am
Andrew EisenNow, having said that, what sites are you reading that are claiming that if "you self-identify as a Gamer, you're immediately the problem" or that gamers are "obligated to stop harassment"? Or was that hyperbole too?09/21/2014 - 1:03am
Andrew EisenFirst of all, ONE person in the Shout box suggested an obligation to call harassers out on their harassing but only after YOU brought it up. Plus, Techno said "when you see it happening." If you don't see it, you're not under any obligation.09/21/2014 - 1:02am
Sleaker@Craig R. - at this point I don't even know what the hashtags are suppsed to be in support of. what does GamerGate actually signify.09/21/2014 - 12:21am
Sleaker@AE - Hyperbole for the first 2, but it seems like some of the comments in the shout are attempting to place blame on fellow gamers because they aren't actively telling people to stop harassing even though they don't necessarily know anyone that has.09/21/2014 - 12:16am
Andrew EisenSleaker - Who the heck are you reading that is claiming "all gamers are bad," we "need to pass laws or judgement on all gamers," that if "you self-identify as a Gamer, you're immediately the problem," or that gamers are "obligated to stop harassment"?09/20/2014 - 9:44pm
erthwjimhe swatted more than just krebs, I think he swatted 30 people http://krebsonsecurity.com/2014/05/teen-arrested-for-30-swattings-bomb-threats/09/20/2014 - 9:31pm
Craig R.Btw, the guy who swatted security expert Brian Krebs? He got picked up recently. It can be done.09/20/2014 - 8:55pm
Craig R.Such things are not done in a vacuum... hence why the 4chan and other logs show what fools you've all been, tricked into doing the trolls' work09/20/2014 - 8:49pm
Sleaker@Technogeek - How do you call someone out that anonymously calls in a SWAT team, or sends threats to people?09/20/2014 - 7:04pm
Technogeek"It also doesn't mean you're obligated to stop harassment from all gamers that are doing so." I'd say you're certainly obligated to call them out when you see it happening.09/20/2014 - 5:17pm
SleakerNow if you disagree with anything in my last 2 posts then we obviously have a difference in world view, and wont come to any sort of agreement. I'm fine with that, maybe some people aren't?09/20/2014 - 5:09pm
 

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