How Gaming Helped AIDS Researchers

September 19, 2011 -

A research paper published Sunday by the journal Nature Structural & Molecular Biology details how the online game Foldit successfully mapped a protein-cutting enzyme from a particular AIDS-like virus found in rhesus monkeys. This enzyme apparently helps the virus spread and to counteract it, its exact molecular structure had to be mapped. This task had been impossible until crowd sourcing came along.

University of Washington chemist Firas Khatib and computer scientist Seth Cooper handled the Foldit program's design and implementation. In a statement issued to the press, Cooper said that people are what truly made the difference in solving this monumental problem.

"People have spatial reasoning skills, something computers are not yet good at. Games provide a framework for bringing together the strengths of computers and humans."

Khatib spoke with Seattle Weekly about the project last night, saying that this breakthrough was "huge" for science more than for aids because it could prove to be helpful to researchers throughout the world who could use the extra help with complex problems.

"This is the first case that were aware of where online gamers solved a scientific problem that hadn't been able to be cracked by all scientific methods developed," Khatib says. "My big hope is that other scientists with challenging problems they can't solve and have been banging their heads over for years will come to us and say 'can you help?'"

Khatib says that Foldit's success comes mostly from being an online competitive game. The game has around 236,000 registered players since it launched in 2008. By putting real-time scores and rankings that change based on how well-designed players make their molecular structures, the program takes advantage of the competitive nature of gaming to accomplish something real.

"If we had just posted it as 'hey, can you help us?' I think we would have gotten a few volunteers and some would have stuck around," Khatib says. "But the fact that there is this competitive aspect, that unleashes a lot more motivation."

The next step, says researchers, is for Foldit players to create new genetic structures related to the Flu virus.

"We want to have players design a protein that will inhibit the flu virus," Khatib says. "This is just the start."

Source: Seattle Weekly


 
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Andrew EisenAh, not linked in the way you (and everyone else) want and expect. That's true.02/27/2015 - 10:06pm
Matthew Wilsonthey are not linked in a way that tracks purchases though. the fact that they have to send a code for the other system shows that they are not linked in the way it counts.02/27/2015 - 9:39pm
Andrew EisenAccounts are already linked. Have been for quite a while. Also, Mario vs. Donkey Kong was announced as a cross-buy title during last January's Nintendo Direct.02/27/2015 - 9:25pm
Matthew Wilsonhttp://www.vg247.com/20…/…/27/olli-olli-3ds-wii-u-cross-buy/ I wounder if this is a sign that Nintendo may finally link accounts across the 3ds/wiiu in the near future.02/27/2015 - 9:18pm
prh99http://www.romanoriginals.co.uk/invt/70931?colour=Blue The dress does comes in white and blue but both have black lace and a sheer back top, I don't see gold or brown. 02/27/2015 - 8:54pm
ZippyDSMleeDungeons was a so bad so good game to me so I been keeping up with its sequel which will more of a Dungeon Keeper clone. As for pre order out of 7 preorders I was not burnt by 2... Add my contempt of most of modern game design.Ya I have all kinds of hurt.02/27/2015 - 8:40pm
MechaTama31I don't even want to know...02/27/2015 - 8:22pm
ZippyDSMleeFun? I can do fun…. I think LOL. Dungeons 2 is on preorder but not via steam... >> Hell I am breaking all kinds of personal butthurt rules to even THINK about pre order...02/27/2015 - 8:12pm
E. Zachary KnightHad some fun discussions about that dumb dress on Facebook. I opened the original picture in GIMP and sampled the colors and determined them to be Blue and Gold. People still say I am wrong.02/27/2015 - 7:41pm
ConsterTime for something completely different: #teamwhiteandgoldllama!02/27/2015 - 7:27pm
ZippyDSMleeAndrew Eisen: I'll try. ^^02/27/2015 - 5:40pm
ZippyDSMlee james_fudge: That’s what I been doing damnit!! *bites your leg*. LOL All but a couple posts have been written in word 2010. This has had my full attention so I’ve been able to keep some consistency up today which is nice a shame it’s still gibberish ><02/27/2015 - 5:38pm
Andrew EisenLike I said, if you want to have a discussion or get a question answered, I'm more than happy to oblige. All I ask in return is you have enough respect for everyone else to take the time to compose a readable post.02/27/2015 - 5:35pm
ZippyDSMleeI suppose it would be poor of me to say this but thank you for taking the time to reply to my questions, it does help me every now and then to discuss things and update or refine my opinion on stuff.. I do miss the forums here….02/27/2015 - 5:31pm
james_fudgeYou could run it through Word :) It's not that hard.02/27/2015 - 5:30pm
ZippyDSMleeSomething’s I can be clearer on more simple constructs making me better understood. Stack my weaknesses with complex constructs and my bad sense of humor and ya it’s a mess.. Consistent clarity is a pain in the butt for me.02/27/2015 - 5:22pm
ZippyDSMleeHave I ever held a covnersion this long that dose not have issues?02/27/2015 - 5:18pm
ZippyDSMleeBetween being learning disabled and having “quirks” from 5th grade I communicate in streaming conscious, I derive information from written words out of order giving me issues revolving around context.02/27/2015 - 5:17pm
Andrew EisenYou're bullshitting. You can communicate clearly. I've seen you do it. If you want to have a discussion, fine. I'm more than happy to oblige but I'm not going to waste any more of my time if you insist on hiding behind the Zippy character.02/27/2015 - 5:15pm
ZippyDSMleeThose that walk the harsh path of grammar are blind to those that nibble upon it. Of course it helps incoherence is my friend…. LOL02/27/2015 - 5:14pm
 

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